Open AccessThe elusive promise of myostatin inhibition for muscular dystrophy
Author(s) -
Kathryn R. Wagner
Publication year - 2020
Publication title -
current opinion in neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 119
eISSN - 1473-6551
pISSN - 1350-7540
DOI - 10.1097/wco.0000000000000853
Subject(s) - myostatin , muscular dystrophy , medicine , clinical trial , duchenne muscular dystrophy , phenotype , bioinformatics , genetics , muscle hypertrophy , biology , gene
Recent terminations of clinical trials of myostatin inhibitors in muscular dystrophy have raised questions about the predictiveness of mouse models for this therapeutic strategy.