Open AccessMR imaging and spectroscopy in degenerative ataxias: toward multimodal, multisite, multistage monitoring of neurodegeneration
Author(s) -
Gülin Öz,
Ian H. Harding,
Janna Krahe,
Kathrin Reetz
Publication year - 2020
Publication title -
current opinion in neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 119
eISSN - 1473-6551
pISSN - 1350-7540
DOI - 10.1097/wco.0000000000000834
Subject(s) - ataxia , neuroscience , neurodegeneration , medicine , magnetic resonance imaging , neurochemical , spinocerebellar ataxia , disease , atrophy , psychology , pathology , radiology
Degenerative ataxias are rare and currently untreatable movement disorders, primarily characterized by neurodegeneration in the cerebellum and brainstem. We highlight MRI studies with the most potential for utility in pending ataxia trials and underscore advances in disease characterization and diagnostics in the field.