Open AccessFactor Consistency of Neuropsychological Test Battery Versions in the NACC Uniform Data Set
Author(s) -
Jessica E. Culhane,
Kwun Chuen Gary Chan,
Merilee Teylan,
YenChi Chen,
Charles Mock,
Kathryn Gauthreaux,
Walter A. Kukull
Publication year - 2020
Publication title -
alzheimer disease and associated disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.213
H-Index - 95
eISSN - 1546-4156
pISSN - 0893-0341
DOI - 10.1097/wad.0000000000000376
Subject(s) - neuropsychology , neuropsychological test , set (abstract data type) , consistency (knowledge bases) , test (biology) , psychology , cognition , clinical psychology , cognitive psychology , computer science , psychiatry , artificial intelligence , paleontology , biology , programming language
The proprietary neuropsychological tests (Form C1) of the National Alzheimer's Coordinating Center (NACC) Uniform Data Set were replaced with nonproprietary versions (Form C2) chosen to closely model their proprietary counterparts. Correlations between analogous test pairs as measured in previous work were good (0.68-0.78), but it is unclear whether the paired tests represent the same set of common factors of cognition or if important factors specific to C1 or C2 only exist. The authors performed multiple factor analysis to analyze correlated C1 and C2 data. They included participants who completed both neuropsychological batteries within 1 year with no change in cognitive status. They found that the C1 and C2 neuropsychological test pairs are strongly related and are represented by the same principal factors. These findings support the use of the C2 test results in conjunction with C1 in longitudinal analyses of NACC data.