Open AccessThe Value of Machine Perfusion Biomarker Concentration in DCD Kidney Transplantations
Author(s) -
E. R. Pieter Hoogland,
Eva E. de Vries,
Maarten H. L. Christiaans,
Björn Winkens,
Maarten Snoeijs,
L. W. Ernest van Heurn
Publication year - 2013
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/tp.0b013e31827908e6
Subject(s) - biomarker , receiver operating characteristic , medicine , lactate dehydrogenase , lipocalin , confidence interval , perfusion , glutathione , urology , gastroenterology , endocrinology , chemistry , biochemistry , enzyme
Donation after cardiac death (DCD) increases the number of donor kidneys but is associated with more primary nonfunction (PNF) and delayed graft function (DGF). It has been suggested that biomarkers in the preservation solution of machine perfused kidneys may predict PNF, although evidence is lacking.