Open AccessEpstein-Barr Virus Gene Expression, Human Leukocyte Antigen Alleles and Chronic High Viral Loads in Pediatric Renal Transplant Patients
Author(s) -
Julie Moran,
Michael J. Carr,
Allison Waters,
Sheila Boyle,
Michael Riordan,
Jeff Connell,
Atif Awan,
William W. Hall,
Jaythoon Hassan
Publication year - 2011
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/tp.0b013e3182247bf2
Subject(s) - bzlf1 , lytic cycle , human leukocyte antigen , biology , immunology , viral load , epstein–barr virus , virology , virus , cytotoxic t cell , antigen , herpesviridae , viral disease , genetics , in vitro
Studies have identified solid organ transplant recipients who remain asymptomatic despite maintaining chronic high Epstein-Barr virus (EBV) viral loads. We examined clinical manifestations, EBV gene expression, human leukocyte antigen (HLA) alleles, and specific T-cell responses to EBV infection in pediatric renal transplant patients.