Open AccessCombined Liver-Kidney Transplants: Allosensitization and Recipient Outcomes
Author(s) -
Medhat Askar,
Jesse D. Schold,
Bijan Eghtesad,
Stuart M. Flechner,
Bruce Kaplan,
Lynne Klingman,
Nizar N. Zein,
John J. Fung,
Titte R. Srinivas
Publication year - 2011
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/tp.0b013e3182184181
Subject(s) - medicine , hazard ratio , contraindication , sensitization , proportional hazards model , kidney , panel reactive antibody , univariate analysis , kidney transplantation , gastroenterology , urology , immunology , multivariate analysis , confidence interval , pathology , alternative medicine
A pretransplant positive crossmatch in combined liver kidney transplants (CLK) is not considered a contraindication based on the reported immunoprotection conferred by the liver allograft. However, antibody-mediated rejection of the kidney in CLK has been reported recently. This prompted our study to investigate the impact of presensitization on CLK recipient outcomes.