Open AccessImmunosuppression Withdrawal After Liver Transplantation: What Are the Next Steps?
Author(s) -
George Mazariegos
Publication year - 2011
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/tp.0b013e31820c85a3
Subject(s) - immunosuppression , liver transplantation , transplantation , medicine , intensive care medicine , biomarker , orthotopic liver transplantation , immunology , surgery , biology , biochemistry
Achieving operational tolerance after liver transplantation remains a challenge for clinicians and scientists. Prospective immunosuppression withdrawal trials coupled with biomarker development and histologic assessment will be critical to the increasing applicability of drug-free transplantation from a sporadic event to a safely achieved, predictable state for increasing numbers of patients.