Open AccessUnique Cellular and Mitochondrial Defects Mediate FK506-Induced Islet β-Cell Dysfunction
Author(s) -
Nassir Rostambeigi,
Ian R. Lanza,
Petras P. Dzeja,
Michael Deeds,
Brian A. Irving,
Honey V. Reddi,
Pranathi Madde,
Zhen Song,
Yan W. Asmann,
Jarett M. Anderson,
Jill M. Schimke,
K. Sreekumaran Nair,
Norman L. Eberhardt,
Yogish C. Kudva
Publication year - 2011
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/tp.0b013e3182094a33
Subject(s) - biology , mitochondrion , viability assay , microbiology and biotechnology , apoptosis , bioenergetics , microarray analysis techniques , programmed cell death , islet , medicine , endocrinology , insulin , gene expression , biochemistry , gene
To determine biological mechanisms involved in posttransplantation diabetes mellitus caused by the immunosuppressant tacrolimus (FK506).