Open AccessDepletion of Alveolar Macrophages Abrogates Prolongation of Cardiac Allograft Survival Induced by Intratracheal Delivery of Alloantigen
Author(s) -
Daiki Iwami,
Qi Zhang,
Osamu Aramaki,
Kenjiro Matsuno,
Katsuya omura,
Nozomu Shirasugi,
Masanori Niimi
Publication year - 2011
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/tp.0b013e3182052b84
Subject(s) - splenocyte , adoptive cell transfer , bronchoalveolar lavage , medicine , spleen , andrology , immunology , transplantation , pathology , lung , immune system , t cell
We previously showed that pretreatment with intratracheal delivery (ITD) of alloantigen induced prolonged cardiac allograft survival and generated regulatory cells in mice. In this study, we examined the role of alveolar macrophages (AM) in our ITD model.