Open AccessDoes a Positive Pretransplant Crossmatch Affect Long-Term Outcome in Liver Transplantation?
Author(s) -
Mohamad R. Al-Sibae,
Alan J. Koffron,
Vandad Raofi
Publication year - 2011
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/tp.0b013e318204758c
Subject(s) - medicine , incidence (geometry) , liver transplantation , transplantation , adverse effect , intensive care medicine , surgery , physics , optics
Despite the historical success of liver transplantation in the face of a positive lymphocytic crossmatch, increased incidence of acute cellular rejection and graft loss have been reported in this setting. Given the potential adverse effects of antirejection treatment, especially in hepatitis C virus-positive recipients, identification of predisposing factors could allow for better surveillance, avoidance of rejection, and potentially better graft outcomes.