Open AccessGenetic Polymorphisms Impact the Risk of Acute Rejection in Pediatric Heart Transplantation: A Multi-Institutional Study
Author(s) -
Diana M. Girnita,
Maria M. Brooks,
Steven A. Webber,
Gilbert J. Burckart,
Robert E. Ferrell,
Gina Zdanowicz,
Susan DeCroo,
Louise Smith,
Richard Chinnock,
Charles E. Canter,
Linda J. Addonizio,
Daniel Bernstein,
James K. Kirklin,
Sarangarajan Ranganathan,
David C. Naftel,
Alin Girnita,
Adriana Zeevi
Publication year - 2008
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/tp.0b013e3181722edc
Subject(s) - proinflammatory cytokine , medicine , transplantation , heart transplantation , vascular endothelial growth factor , gastroenterology , immunology , vegf receptors , inflammation
The objective of this study was to determine the association between the genetic polymorphisms of proinflammatory and regulatory cytokines and long-term rates of repeat and late acute rejection episodes in pediatric heart transplant (PHTx) recipients.