HLA Mismatches Remain Risk Factors for Acute Kidney Allograft Rejection in Patients Receiving Quadruple Immunosuppression With Anti-Interleukin-2 Receptor Antibodies | Zendy

Karl Martin Wissing | Zendy; Guy Fomegné | Zendy; Nilüfer Broeders | Zendy; Lidia Ghisdal | Zendy; Anh Hoang | Zendy; Dimitri Mikhalski | Zendy; Vincent Donckier | Zendy; P Vereerstraeten | Zendy; Daniel Abramowicz | Zendy

Open Access

HLA Mismatches Remain Risk Factors for Acute Kidney Allograft Rejection in Patients Receiving Quadruple Immunosuppression With Anti-Interleukin-2 Receptor Antibodies

Author(s) -

Karl Martin Wissing,

Guy Fomegné,

Nilüfer Broeders,

Lidia Ghisdal,

Anh Hoang,

Dimitri Mikhalski,

Vincent Donckier,

P Vereerstraeten,

Daniel Abramowicz

Publication year - 2008

Publication title -

transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.45

H-Index - 204

eISSN - 1534-6080

pISSN - 0041-1337

DOI - 10.1097/tp.0b013e31816349b5

Subject(s) - medicine , daclizumab , basiliximab , tacrolimus , immunosuppression , calcineurin , transplantation , dialysis , kidney transplantation , panel reactive antibody , belatacept , mycophenolic acid , human leukocyte antigen , immunology , gastroenterology , antigen , kidney transplant

New immunosuppressive drugs such as anti-interleukin-2 receptor antibodies (aIL2R) and mycophenolate mofetil (MMF) have reduced the incidence of acute rejection after renal transplantation. Whether matching donor and recipient human leukocyte antigen (HLA) antigens is still relevant in patients receiving modern immunosuppression has been questioned.

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