Open AccessExtracellular Vesicles Released During Normothermic Machine Perfusion Are Associated With Human Donor Kidney Characteristics
Author(s) -
Wouter W. Woud,
Asel Arykbaeva,
Ian Alwayn,
Carla C. Baan,
Robert C. Minnee,
Martin J. Hoogduijn,
Karin de Boer
Publication year - 2022
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/tp.0000000000004215
Subject(s) - nanoparticle tracking analysis , machine perfusion , flow cytometry , cd63 , chemistry , transplantation , tetraspanin , cd31 , kidney transplantation , kidney , cd81 , microbiology and biotechnology , microvesicles , perfusion , andrology , biophysics , biology , immunology , biochemistry , medicine , cell , in vitro , surgery , gene , microrna , hepatitis c virus , virus , liver transplantation
Extracellular vesicles (EVs) are tissue-specific particles released by cells containing valuable diagnostic information in the form of various biomolecules. The characterization of EVs released by kidney grafts during normothermic machine perfusion (NMP) may present a promising avenue to assess graft status before transplantation.