Open AccessOutcomes of SARS-CoV-2 Infection in Unvaccinated Compared With Vaccinated Solid Organ Transplant Recipients: A Propensity Matched Cohort Study
Author(s) -
Victoria Hall,
Ghadeer Al-Alahmadi,
Javier T. Solera,
Tina Marinelli,
Héloïse Cardinal,
G. V. Ramesh Prasad,
Sacha A. De Serres,
Debra Isaac,
Rahul Mainra,
Caroline Lamarche,
Ruth SapirPichhadze,
Susan Gilmour,
John Matelski,
Atul Humar,
Deepali Kumar
Publication year - 2022
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/tp.0000000000004178
Subject(s) - medicine , vaccination , cohort , propensity score matching , logistic regression , cohort study , immunology
Solid organ transplant (SOT) recipients are at high risk for complications from coronavirus disease 2019 (COVID-19). Vaccination may mitigate this risk; however, immunogenicity appears to be significantly impaired, with reports of increased risk of breakthrough infection. It is unknown if vaccine breakthrough infections are milder or as severe as infections in unvaccinated patients.