Open AccessCT-measured Cortical Volume Ratio Is an Accurate Alternative to Nuclear Medicine Split Scan Ratio Among Living Kidney Donors
Author(s) -
John R. Montgomery,
Craig S. Brown,
Allyse Zondlak,
Kevin W. Walsh,
Julia E Kozlowski,
Alexa M Pinsky,
Emily A Herriman,
Jeremy B. Sussman,
Yee Lu,
Erica B. Stein,
Prasad R. Shankar,
Randall S. Sung,
Kenneth J. Woodside
Publication year - 2021
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/tp.0000000000003676
Subject(s) - renal function , medicine , confidence interval , kidney , nuclear medicine , urology , mathematics
The 125I-iothalamate clearance and 99mTc diethylenetriamine-pentaacetic acid (99mTc-DTPA) split scan nuclear medicine studies are used among living kidney donor candidates to determine measured glomerular filtration rate (mGFR) and split scan ratio (SSR). The computerized tomography-derived cortical volume ratio (CVR) is a novel measurement of split kidney function and can be combined with predonation estimated GFR (eGFR) or mGFR to predict postdonation kidney function. Whether predonation SSR predicts postdonation kidney function better than predonation CVR and whether predonation mGFR provides additional information beyond predonation eGFR are unknown.