Open AccessTorque Teno Virus Load Is Associated With Subclinical Alloreactivity in Kidney Transplant Recipients: A Prospective Observational Trial
Author(s) -
Konstantin Doberer,
Frederik Haupenthal,
Maja Nackenhorst,
Florian Bauernfeind,
Florentina Dermuth,
Michael Eigenschink,
Martin Schiemann,
Johannes Kläger,
Irene Görzer,
Farsad Eskandary,
Roman ReindlSchwaighofer,
Željko Kikić,
Georg A. Böhmig,
Robert Straßl,
Heinz Regele,
Elisabeth PuchhammerStöckl,
Gregor Bond
Publication year - 2021
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/tp.0000000000003619
Subject(s) - immunosuppression , subclinical infection , torque teno virus , medicine , kidney transplantation , context (archaeology) , viral load , gastroenterology , transplantation , confidence interval , prospective cohort study , immunology , virus , biology , genotype , paleontology , biochemistry , gene
Nonpathogenic torque teno viruses (TTVs) are highly prevalent in transplant recipients and associated with immunosuppression. Studies in kidney transplant patients have proposed assessment of TTV load for risk stratification of clinically overt graft rejection. The value of TTV quantification in the context of subclinical rejection has not been evaluated.