Open AccessCorrelation of Glomerular Size With Donor–Recipient Factors and With Response to Injury
Author(s) -
Joseph P. Grande,
Erika S. Helgeson,
Arthur J. Matas
Publication year - 2021
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/tp.0000000000003570
Subject(s) - medicine , renal function , hazard ratio , urology , biopsy , glomerulosclerosis , kidney , kidney transplantation , prospective cohort study , kidney disease , focal segmental glomerulosclerosis , cohort , renal biopsy , gastroenterology , pathology , glomerulonephritis , proteinuria , confidence interval
Glomerular size in renal allografts is impacted by donor-recipient factors and response to injury. In serial biopsies of patients with well-functioning grafts, increased glomerular size correlates with better survival. However, no previous study has addressed the association of glomerular size at the time of a for-cause biopsy and clinical/histopathologic markers of injury, or effect on long-term graft outcome.