Open AccessGalectin-3 and Risk of Late Graft Failure in Kidney Transplant Recipients: A 10-year Prospective Cohort Study
Author(s) -
Camilo G. Sotomayor,
Charlotte A Te Velde-Keyzer,
Arjan Diepstra,
Marco van Londen,
Robert A. Pol,
Adrian Post,
Rijk O. B. Gans,
Ilja M. Nolte,
Riemer Slart,
Martin H. de Borst,
Stefan P. Berger,
Ramón Rodrigo,
Gerjan Navis,
Rudolf A. de Boer,
Stephan J. L. Bakker
Publication year - 2020
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/tp.0000000000003359
Subject(s) - interquartile range , medicine , hazard ratio , proportional hazards model , dialysis , prospective cohort study , kidney transplantation , cohort , confidence interval , transplantation , cohort study , surgery
Galectin-3 may play a causal role in kidney inflammation and fibrosis, which may also be involved in the development of kidney graft failure. With novel galectin-3-targeted pharmacological therapies increasingly coming available, we aimed to investigate whether galectin-3 is associated with risk of late graft failure in kidney transplant recipients (KTR).