Open AccessBK Polyomavirus-specific T Cells as a Diagnostic and Prognostic Marker for BK Polyomavirus Infections After Pediatric Kidney Transplantation
Author(s) -
Thurid Ahlenstiel-Grunow,
Martina Sester,
Urban Sester,
Hans H. Hirsch,
Lars Pape
Publication year - 2020
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/tp.0000000000003133
Subject(s) - medicine , immunosuppression , kidney transplantation , transplantation , bk virus , biopsy , cd8 , virology , immunology , immune system
After kidney transplantation, uncontrolled BK polyomavirus (BKPyV) replication causes kidney graft failure through BKPyV-associated nephropathy (BKPyVAN), but markers predicting outcome are missing. BKPyV-specific T cells may serve as a predictive marker to identify patients at risk of persistent DNAemia and BKPyVAN.