Open AccessProtocol Biopsies in Patients With Subclinical De Novo Donor-specific Antibodies After Kidney Transplantation: A Multicentric Study
Author(s) -
Dominique Bertrand,
Philippe Gatault,
Maïté Jauréguy,
Cyril Garrouste,
Johnny Sayegh,
Nicolas Bouvier,
Sophie Caillard,
Luca Lanfranco,
Aliénor Galinier,
Charlotte Laurent,
Isabelle Étienne,
Fabienne Farce,
François Audigier,
Dominique Guerrot
Publication year - 2019
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/tp.0000000000003055
Subject(s) - medicine , subclinical infection , biopsy , renal function , urology , kidney , donor specific antibodies , kidney transplantation , transplantation , renal biopsy , immunosuppression , proteinuria , gastroenterology , surgery
De novo donor-specific antibodies (DSAs) are associated with antibody-mediated rejection (AMR) and allograft loss. Whether monitoring of de novo DSA (dnDSA) paired with systematic kidney biopsy should become routine remains to be established.