Open AccessPractical Considerations for APOL1 Genotyping in the Living Kidney Donor Evaluation
Author(s) -
Alejandra MenaGutierrez,
Amber ReevesDaniel,
Colleen L. Jay,
Barry I. Freedman
Publication year - 2020
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/tp.0000000000002933
Subject(s) - medicine , genotyping , nephropathy , kidney , kidney transplantation , kidney disease , genotype , nephrectomy , intensive care medicine , biology , genetics , gene , endocrinology , diabetes mellitus
Association between the apolipoprotein L1 gene (APOL1) and nephropathy has altered the epidemiology of chronic kidney disease. In addition, donor APOL1 genotypes play important roles in the time to allograft failure in kidneys transplanted from deceased donors and the safety of living kidney donation.