Open AccessMetformin Attenuates Cyclosporine A-induced Renal Fibrosis in Rats
Author(s) -
Can-Xiang Lin,
Li Yan,
Liang Shi,
Jun Tao,
Lisui Zhang,
YuJih Su,
Yi Huang,
Zongkai Zhao,
Shanying Liu,
Junmeng Zheng
Publication year - 2019
Publication title -
transplantation
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/tp.0000000000002864
Subject(s) - metformin , nephrotoxicity , medicine , creatinine , blood urea nitrogen , kidney , fibrosis , renal function , endocrinology , glomerulosclerosis , pharmacology , proteinuria , urology , diabetes mellitus
The aim of the present study was to investigate the therapeutic potential of metformin in preventing cyclosporine A (CsA)-induced nephrotoxicity.