Open AccessAssociation Between Living Kidney Donor Postdonation Hypertension and Recipient Graft Failure
Author(s) -
Courtenay M. Holscher,
Tanveen Ishaque,
Christine E. Haugen,
Kyle R. Jackson,
Jacqueline Garonzik-Wang,
Yifan Yu,
Fawaz Al Ammary,
Dorry L. Segev,
Allan B. Massie
Publication year - 2020
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/tp.0000000000002832
Subject(s) - medicine , hazard ratio , proportional hazards model , blood pressure , diabetes mellitus , confidence interval , surgery , gastroenterology , endocrinology
Recipients of kidneys from living donors who subsequently develop end-stage renal disease (ESRD) also have higher graft failure, suggesting the 2 donor kidneys share risk factors that could inform recipient outcomes. Given that donor ESRD is rare, an earlier and more common postdonation outcome could serve as a surrogate to individualize counseling and management for recipients. Hypertension is a frequent event before donor ESRD; thus, early postdonation hypertension might indicate higher risk of graft failure.