Open AccessTubular Ectasia in Renal Allograft Biopsy: Associations With Occult Obstructive Urological Complications
Author(s) -
Marija Bojić,
Heinz Regele,
Harald Herkner,
Gabriela Berlakovich,
Johannes Kläger,
Carina Bauer,
Christian Seitz,
Željko Kikić
Publication year - 2020
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/tp.0000000000002699
Subject(s) - medicine , occult , biopsy , ectasia , renal function , renal biopsy , receiver operating characteristic , radiology , urology , pathology , alternative medicine
Urological obstructive complications (UOC) affect up to 15% of kidney transplants (KTX). Most cases are excluded by ultrasonography (US); however, accuracy may be limited in the early transplant phase. Features of acute tubular injury (ATI) in KTX biopsy may be informative but histological features indicating UOC are ill defined. Tubular ectasia (TE) was shown to be associated with UOC in experimental data. We evaluated the association of histomorphological features, particularly TE, with occult (=without relevant hydronephrosis in US) UOC and renal outcomes.