Open AccessTandem Orthotopic Living Donor Liver Transplantation Followed by Same Donor Haploidentical Hematopoietic Stem Cell Transplantation for DOCK8 Deficiency
Author(s) -
Alexandra F. Freeman,
Nada Yazigi,
Nirali N. Shah,
David E. Kleiner,
Mark Parta,
Prescott Atkinson,
Theo Heller,
Steven M. Holland,
Stuart S. Kaufman,
Khalid Khan,
Dennis D. Hickstein
Publication year - 2019
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/tp.0000000000002649
Subject(s) - medicine , hematopoietic stem cell transplantation , immunosuppression , transplantation , stem cell , immunology , gastroenterology , biology , genetics
An 11-year-old girl with dedicator of cytokinesis 8 (DOCK8) deficiency was proposed for potentially curative hematopoietic stem cell transplantation (HSCT), the donor being her haploidentical mother. However, end-stage liver disease caused by chronic Cryptosporidium infection required liver transplantation before HSCT.