Open AccessPreservation of Microvascular Integrity in Murine Orthotopic Tracheal Allografts by Clopidogrel
Author(s) -
Christian Heim,
Mohammad Afzal Khan,
Benjamin von Silva-Tarouca,
A. Kuckhahn,
Thomas Stamminger,
M. Ramsperger-Gleixner,
Mark R. Nicolls,
Michael Weyand,
Stephan Ensminger
Publication year - 2019
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/tp.0000000000002571
Subject(s) - lamina propria , cd31 , medicine , pathology , clopidogrel , immunohistochemistry , epithelium , aspirin
Survival after lung transplantation is mainly limited by the development of chronic lung allograft dysfunction (CLAD). The aim of this study was to investigate if platelet inhibition by clopidogrel has a functionally relevant influence on the microvascular integrity of orthotopic tracheal allografts as an anatomic basis for the development of CLAD.