Open AccessPotentiating Renal Regeneration Using Mesenchymal Stem Cells
Author(s) -
Lauren Brasile,
Nicholas Henry,
Giuseppe Orlando,
Bart M. Stubenitsky
Publication year - 2019
Publication title -
transplantation
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/tp.0000000000002455
Subject(s) - mesenchymal stem cell , kidney , transplantation , regeneration (biology) , ex vivo , stem cell , paracrine signalling , medicine , biology , microbiology and biotechnology , pathology , in vivo , receptor
The potential of a mesenchymal stem cell (MSC) therapy to accelerate the repair of ischemically damaged human kidneys during 24 hours of warm perfusion was evaluated. The hypothesis was that by administering MSC directly to the renal tissue, there would be an improved opportunity for cellular repair mediated by intrarenal paracrine effects.