Open AccessReduced Risk of BK Polyomavirus Infection in HLA-B51–positive Kidney Transplant Recipients
Author(s) -
Herman F. Wunderink,
Geert W. Haasnoot,
Caroline S. de Brouwer,
Erik W. van Zwet,
A.C.M. Kroes,
Johan W. de Fijter,
Joris I. Rotmans,
Frans H.J. Claas,
Mariet C.W. Feltkamp
Publication year - 2019
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/tp.0000000000002376
Subject(s) - viremia , human leukocyte antigen , bk virus , kidney transplantation , immunology , virology , transplantation , medicine , epitope , hazard ratio , concordance , biology , antigen , confidence interval , virus
Identification of specific HLA alleles and T-cell epitopes that influence the course of BK polyomavirus (BKPyV) infection after kidney transplantation (KTx), including development of BKPyV-associated nephropathy (BKPyVAN), can be useful for patient risk stratification and possibly vaccine development.