Open AccessEfficacy of IgM-enriched Immunoglobulin for Vasopressor-resistant Vasoplegic Shock After Liver Transplantation
Author(s) -
Katharina Willuweit,
Dmitri Bezinover,
Kerstin Herzer,
Karol Nowak,
Andreas Paul,
Fuat H. Saner
Publication year - 2019
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/tp.0000000000002344
Subject(s) - medicine , procalcitonin , liver transplantation , transplantation , inotrope , sepsis , gastroenterology , septic shock , shock (circulatory) , anesthesia
Vasoplegia is a clinical condition typically manifested by cardiovascular instability unresponsive to the usual doses of inotropes or vasopressors. It can occur in a variety of clinical settings including liver transplantation (LT). Immunoglobulins have been used to treat sepsis-related vasoplegia. We performed a retrospective study to evaluate the efficacy of IgM-enriched immunoglobulin (IgMIg) on 30-day mortality and its ability to reverse vasoplegia in patients undergoing LT.