Open AccessFrailty, Inflammatory Markers, and Waitlist Mortality Among Patients With End-stage Renal Disease in a Prospective Cohort Study
Author(s) -
Mara McAdamsDeMarco,
Ying Hua,
Alvin G. Thomas,
Fatima Warsame,
Ashton A. Shaffer,
Christine E. Haugen,
Jacqueline Garonzik-Wang,
Niraj M. Desai,
Ravi Varadhan,
Jeremy Walston,
Silas P. Norman,
Dorry L. Segev
Publication year - 2018
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/tp.0000000000002213
Subject(s) - medicine , end stage renal disease , cohort , c reactive protein , population , confidence interval , prospective cohort study , kidney disease , cohort study , disease , inflammation , environmental health
Among community-dwelling older adults, frailty is associated with heightened markers of inflammation and subsequent mortality. Although frailty is common among end-stage renal disease (ESRD) patients, the role of frailty and markers of inflammation in this population remains unclear. We quantified these associations in patients on the kidney transplant waitlist and tested whether frailty and/or markers of inflammation improve waitlist mortality risk prediction.