Open AccessDonor Club Cell Secretory Protein G38A Polymorphism Is Associated With a Decreased Risk of Primary Graft Dysfunction in the French Cohort in Lung Transplantation
Author(s) -
Angela Hin,
Caroline Kannengiesser,
Arnaud Roussel,
B. Renaud-Picard,
Antoine Roux,
Martine ReynaudGaubert,
Johanna Claustre,
Adrien Tissot,
R. Guillemain,
JeanFrançois Mornex,
Sacha Mussot,
C. Dromer,
Marcel Dahan,
Olivier Brugière,
Olaf Mercier,
R. Borie,
Marina Pretolani,
Yves Castier,
Pierre Mordant
Publication year - 2018
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/tp.0000000000002143
Subject(s) - club , lung transplantation , cohort , medicine , transplantation , lung , cohort study , cell , immunology , oncology , biology , genetics , anatomy
Club Cell Secretory Protein (CCSP) G38A polymorphism has recently been involved in lung epithelial susceptibility to external injuries. Lung transplantation (LT) is currently limited by ischemia-reperfusion injury leading to primary graft dysfunction (PGD). We thus hypothesized that donor CCSP G38A polymorphism might impact the risk of PGD after LT.