Open AccessComparison of BQ123, Epoprostenol, and Verapamil as Vasodilators During Normothermic Ex Vivo Liver Machine Perfusion
Author(s) -
Juan Echeverri,
Nicolás Goldaracena,
J. Moritz Kaths,
Ivan Linares,
Roizar Roizales,
Dagmar Kollmann,
Mátyás Hamar,
Peter Urbanellis,
Sujani Ganesh,
Oyedele Adeyi,
Mahmood Tazari,
Markus Selzner,
Nazia Selzner
Publication year - 2018
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/tp.0000000000002021
Subject(s) - verapamil , medicine , perfusion , vasodilation , anesthesia , ex vivo , in vivo , calcium , biology , microbiology and biotechnology
The optimal vasodilator to avoid hepatic artery vasospasm during normothermic ex vivo liver perfusion (NEVLP) is yet to be determined. We compared safety and efficacy of BQ123 (endothelin1 antagonist), epoprostenol (prostacyclin analogue), and verapamil (calcium channel antagonist).