Open AccessLymphocyte Depletion After Alemtuzumab Induction Disrupts Intestinal Fungal Microbiota in Cynomolgus Monkeys
Author(s) -
Qiurong Li,
Chenyang Wang,
Chunbo Tang,
Qi He,
Jieshou Li
Publication year - 2014
Publication title -
transplantation
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/tp.0000000000000373
Subject(s) - biology , candida albicans , microbiology and biotechnology , immune system , gut flora , immunology , lymphocyte , population , demography , sociology
The interactions of specific fungal phylotypes with immune cells have been recently documented; however, little is known whether gut fungal microbiota is influenced by aberrant immune response in immunosuppressive state. This study aimed to define the biologic impact of lymphocyte depletion on gut fungal microbiota and their relationship.