Open AccessRapid detection of platelet inhibition and dysfunction in traumatic brain injury: A prospective observational study
Author(s) -
Jurgis Alvikas,
Mazen Zenati,
Insiyah Campwala,
J. R. C. Jansen,
Adnan Hassoune,
Heather Phelos,
David O. Okonkwo,
Matthew D. Neal
Publication year - 2021
Publication title -
the journal of trauma and acute care surgery
Language(s) - English
Resource type - Journals
eISSN - 2163-0763
pISSN - 2163-0755
DOI - 10.1097/ta.0000000000003427
Subject(s) - medicine , interquartile range , clopidogrel , platelet , aspirin , platelet transfusion , platelet activation , intensive care unit , anesthesia
Rapid platelet function testing is frequently used to determine platelet function in patients with traumatic intracranial hemorrhage (tICH). Accuracy and clinical significance of decreased platelet response detected by these tests is not well understood. We sought to determine whether VerifyNow and whole blood aggregometry (WBA) can detect poor platelet response and to elucidate its clinical significance for tICH patients.