Open AccessDose-dependent association between blood transfusion and nosocomial infections in trauma patients: A secondary analysis of patients from the PAMPer trial
Author(s) -
Husayn A Ladhani,
Vanessa P. Ho,
C Clare Charbonnet,
Jason L. Sperry,
Francis X Guyette,
Joshua B. Brown,
Brian Daley,
Richard S. Miller,
Brian G. Harbrecht,
Herb A. Phelan,
Jeffrey A. Claridge
Publication year - 2021
Publication title -
the journal of trauma and acute care surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.25
H-Index - 187
eISSN - 2163-0763
pISSN - 2163-0755
DOI - 10.1097/ta.0000000000003251
Subject(s) - medicine , blood transfusion , emergency medicine , intensive care medicine
The Prehospital Air Medical Plasma (PAMPer) trial demonstrated a survival benefit to trauma patients who received thawed plasma as part of early resuscitation. The objective of our study was to examine the association between blood transfusion and nosocomial infections among trauma patients who participated in the PAMPer trial. We hypothesized that transfusion of blood products will be associated with the development of nosocomial infections in a dose-dependent fashion.