Open AccessDistinct immunologic endotypes are associated with clinical trajectory after severe blunt trauma and hemorrhagic shock
Author(s) -
Scott C. Brakenridge,
Zhongkai Wang,
Michael C. Cox,
Steven L. Raymond,
Russell B. Hawkins,
Dijoia B Darden,
Gabriela Ghita,
Babette Brumback,
Joseph Cuschieri,
Ronald V. Maier,
Frederick A. Moore,
Alicia M. Mohr,
Philip A. Efron,
Lyle L. Moldawer
Publication year - 2020
Publication title -
the journal of trauma and acute care surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.25
H-Index - 187
eISSN - 2163-0763
pISSN - 2163-0755
DOI - 10.1097/ta.0000000000003029
Subject(s) - medicine , endotype , incidence (geometry) , cohort , immunology , prospective cohort study , blunt trauma , immune system , surgery , disease , physics , optics
The genomic/cytokine "storm" after severe trauma is well described. However, the differing composition, magnitude and resolution of this response, and its relationship to clinical outcomes remain unclear.