Open AccessA systematic review and meta-analysis of traumatic intracranial hemorrhage in patients taking prehospital antiplatelet therapy: Is there a role for platelet transfusions?
Author(s) -
Jurgis Alvikas,
Sara P. Myers,
Charles B. Wessel,
David O. Okonkwo,
Bellal Joseph,
Carlos A. Peláez,
Curtis E. Doberstein,
Andrew Guillotte,
Matthew R. Rosengart,
Matthew D. Neal
Publication year - 2020
Publication title -
the journal of trauma and acute care surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.25
H-Index - 187
eISSN - 2163-0763
pISSN - 2163-0755
DOI - 10.1097/ta.0000000000002640
Subject(s) - medicine , meta analysis , platelet transfusion , odds ratio , subgroup analysis , randomized controlled trial , confidence interval , platelet
Platelet transfusion has been utilized to reverse platelet dysfunction in patients on preinjury antiplatelets who have sustained a traumatic intracranial hemorrhage (tICH); however, there is little evidence to substantiate this practice. The objective of this study was to perform a systematic review on the impact of platelet transfusion on survival, hemorrhage progression and need for neurosurgical intervention in patients with tICH on prehospital antiplatelet medication.