Open AccessThe gut microbiome distinguishes mortality in trauma patients upon admission to the emergency department
Author(s) -
David M. Burmeister,
Taylor Johnson,
Zhao Lai,
Shan Scroggins,
Mark DeRosa,
Rachelle B. Jonas,
Caroline Zhu,
Elizabeth Scherer,
Ronald M Stewart,
Martin G. Schwacha,
Donald H. Jenkins,
Brian J. Eastridge,
Susannah Nicholson
Publication year - 2020
Publication title -
the journal of trauma and acute care surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.25
H-Index - 187
eISSN - 2163-0763
pISSN - 2163-0755
DOI - 10.1097/ta.0000000000002612
Subject(s) - medicine , emergency department , observational study , intensive care unit , body mass index , blunt trauma , population , sepsis , penetrating trauma , prospective cohort study , population study , emergency medicine , blunt , surgery , environmental health , psychiatry
Traumatic injury can lead to a compromised intestinal epithelial barrier, decreased gut perfusion, and inflammation. While recent studies indicate that the gut microbiome (GM) is altered early following traumatic injury, the impact of GM changes on clinical outcomes remains unknown. Our objective of this follow-up study was to determine if the GM is associated with clinical outcomes in critically injured patients.