Open AccessSmall Fiber Polyneuropathy Is Associated With Non–Bladder-Centric Interstitial Cystitis/Bladder Pain Syndrome Patients
Author(s) -
Tyler Overholt,
Catherine A. Matthews,
Robert J. Evans,
Gopal Badlani,
Christine S. Ahn,
Trang Simon,
Stephen J. Walker
Publication year - 2020
Publication title -
female pelvic medicine and reconstructive surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.648
H-Index - 28
eISSN - 2154-4212
pISSN - 2151-8378
DOI - 10.1097/spv.0000000000000972
Subject(s) - interstitial cystitis , medicine , fibromyalgia , urology , bladder pain syndrome , urinary bladder , nerve fiber , urinary system , psychiatry
Interstitial cystitis/bladder pain syndrome (IC/BPS) comprises at least 2 phenotypes. Bladder centric patients typically demonstrate low bladder capacity (BC), often with Hunner lesion (HL), whereas non-bladder-centric patients typically have normal cystoscopic findings and more co-occurring nonurologic symptoms/syndromes (NUS), contributing to widespread pain beyond the bladder. Small fiber polyneuropathy (SFPN) is significantly associated with fibromyalgia, a frequent IC/BPS codiagnosis and may play an etiologic role in IC/BPS. We assessed SFPN status in bladder-centric versus non-bladder-centric IC/BPS patients.