Open AccessThe Impact of Molecular Subtyping on Pathological Staging of Pancreatic Cancer
Author(s) -
Stephan Dreyer,
S. Rae,
Kirsty Bisset,
Rosie Upstill-Goddard,
Georgios Gemenetzis,
Amber Johns,
Euan J. Dickson,
Anubhav Mittal,
Anthony J. Gill,
Fraser Duthie,
Antonio Pea,
Rita T. Lawlor,
Aldo Scarpa,
Roberto Salvia,
Alessandra Pulvirenti,
Alessandro Zerbi,
Federica Marchesi,
Colin McKay,
Andrew V. Biankin,
Jaswinder S. Samra,
David K. Chang,
Nigel B. Jamieson
Publication year - 2023
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/sla.0000000000005050
Subject(s) - medicine , subtyping , hazard ratio , pancreatectomy , pathological , oncology , pancreatic cancer , pathological staging , surgical margin , adenocarcinoma , cancer , confidence interval , pathology , pancreas , computer science , programming language
The long-term outcomes following surgical resection for pancreatic ductal adenocarcinoma (PDAC) remains poor, with only 20% of patients surviving 5 years after pancreatectomy. Patient selection for surgery remains suboptimal largely due to the absence of consideration of aggressive tumor biology.