Open AccessOea Signaling Pathways and the Metabolic Benefits of Vertical Sleeve Gastrectomy
Author(s) -
Chelsea R. Hutch,
Danielle R. Trakimas,
Karen J. Roelofs,
Joshua W. Pressler,
Joyce Sorrell,
Daniela Cota,
Silvana Obici,
Darleen A. Sandoval
Publication year - 2020
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/sla.0000000000003093
Subject(s) - cd36 , endocrinology , medicine , type 2 diabetes , triglyceride , peroxisome proliferator activated receptor , receptor , diabetes mellitus , cholesterol
The aim of this study was to determine whether downstream [peroxisome proliferator-activated-receptor alpha (PPARα) and the G-protein coupled receptor, GPR119] and upstream (a fatty acid translocase, CD36) signaling targets of N-oleoylethanolamide (OEA) were necessary for weight loss, metabolic improvements, and diet preference following vertical sleeve gastrectomy (VSG).