Open AccessDeleterious Effect of RAS and Evolutionary High-risk TP53 Double Mutation in Colorectal Liver Metastases
Author(s) -
Yun Shin Chun,
Guillaume Passot,
Satoshi Yamashita,
Maliha Nusrat,
Panagiotis Katsonis,
Jonathan M. Loree,
Claudius Conrad,
Ching Wei D. Tzeng,
Lianchun Xiao,
Thomas A. Aloia,
Cathy Eng,
Scott Kopetz,
Olivier Lichtarge,
Jean Nicolas Vauthey
Publication year - 2019
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/sla.0000000000002450
Subject(s) - medicine , kras , hazard ratio , missense mutation , colorectal cancer , concomitant , oncology , mutation , germline mutation , confidence interval , gastroenterology , gene , cancer , genetics , biology
To assess the impact of somatic gene mutations on survival among patients undergoing resection of colorectal liver metastases (CLM).