Open AccessHypobaria Exposure Worsens Cardiac Function and Endothelial Injury in AN Animal Model of Polytrauma: Implications for Aeromedical Evacuation
Author(s) -
Kerri Lopez,
Andrew Suen,
Yang Yang,
Sheng Wang,
Brittney Williams,
Jing Zhu,
Jiang Hu,
Gary Fiskum,
Alan S. Cross,
Rosemary A. Kozar,
Catriona Miller,
Lin Zou,
Wei Chao
Publication year - 2020
Publication title -
shock
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.095
H-Index - 117
eISSN - 1540-0514
pISSN - 1073-2322
DOI - 10.1097/shk.0000000000001716
Subject(s) - polytrauma , medicine , anesthesia , acute kidney injury , surgery
Aeromedical evacuation can expose traumatically injured patients to low pressure (hypobaria) and hypoxia. Here, we sought to assess the impact of hypobaria on inflammation, organ injury, and mortality in a mouse model of polytrauma.