Open AccessShould Albumin be Considered for Prehospital Resuscitation in Austere Environments? A Prospective Randomized Survival Study in Rabbits
Author(s) -
Bijan S. Kheirabadi,
Nahir Miranda,
Irasema B Terrazas,
Amber N. Voelker,
Rodolfo de Guzman,
Nathan Wienandt,
A. C. Brown,
Michael A. Dubick
Publication year - 2019
Publication title -
shock
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.095
H-Index - 117
eISSN - 1540-0514
pISSN - 1073-2322
DOI - 10.1097/shk.0000000000001480
Subject(s) - medicine , hematocrit , albumin , resuscitation , blood volume , anesthesia , mean arterial pressure , blood pressure , shock (circulatory) , fresh frozen plasma , whole blood , surgery , platelet , heart rate
The new guidelines for prehospital care of combat casualties in shock recommend administration of whole blood or blood components to increase blood pressure to a permissible hypotensive level (i.e., hypotensive resuscitation [HR]). We investigated if 2 h of HR using limited volumes of whole blood, plasma, or albumin would lead to full recovery and long-term survival of rabbits subjected to severe hemorrhagic shock (HS).