Open AccessCardiac Glucose and Fatty Acid Transport After Experimental Mono- and Polytrauma
Author(s) -
Ina Lackner,
Birte Weber,
Deborah Knecht,
Klemens Horst,
Borna Relja,
Florian Gebhard,
Hans-Christian Pape,
Markus HuberLang,
Frank Hildebrand,
Miriam Kalbitz
Publication year - 2020
Publication title -
shock
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.095
H-Index - 117
eISSN - 1540-0514
pISSN - 1073-2322
DOI - 10.1097/shk.0000000000001400
Subject(s) - polytrauma , fatty acid , glucose transporter , glycogen , medicine , endocrinology , chemistry , biochemistry , surgery , insulin
The aim of this study was to define the influence of trauma on cardiac glucose and fatty acid transport. The effects were investigated in vivo in a porcine mono- and polytrauma model and in vitro in human cardiomyocytes, which were treated simultaneously with different inflammatory substances, mimicking posttraumatic inflammatory conditions.