Open AccessHydrocortisone, Ascorbic Acid, and Thiamine (HAT) Therapy Decreases Oxidative Stress, Improves Cardiovascular Function, and Improves Survival in Murine Sepsis
Author(s) -
Jiyoun Kim,
Leen Arnaout,
Daniel G. Remick
Publication year - 2020
Publication title -
shock
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.095
H-Index - 117
eISSN - 1540-0514
pISSN - 1073-2322
DOI - 10.1097/shk.0000000000001385
Subject(s) - oxidative stress , medicine , sepsis , ascorbic acid , survival rate , andrology , endocrinology , gastroenterology , chemistry , food science
A small clinical trial showed HAT therapy improved survival but no studies have been reported in animal models to examine potential mechanisms.