Open AccessThe Association of Fever and Antipyretic Medication With Outcomes in Mechanically Ventilated Patients: A Cohort Study
Author(s) -
Emily Evans,
Rebecca Doctor,
Brian F. Gage,
Richard S. Hotchkiss,
Brian M. Fuller,
Anne M. Drewry
Publication year - 2019
Publication title -
shock
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.095
H-Index - 117
eISSN - 1540-0514
pISSN - 1073-2322
DOI - 10.1097/shk.0000000000001368
Subject(s) - medicine , antipyretic , hazard ratio , mechanical ventilation , intensive care unit , confidence interval , sepsis , proportional hazards model , cohort , cohort study , retrospective cohort study , emergency department , intensive care , anesthesia , intensive care medicine , analgesic , psychiatry
Fever is common in mechanically ventilated patients and may be uniquely detrimental in those with lung injury because of its injurious effects on pulmonary vascular permeability and alveolar epithelium. We evaluated the association of fever and antipyretic medication with mortality in mechanically ventilated emergency department (ED) patients.