Open AccessHeparin-Binding Protein as a Prognostic Biomarker of Sepsis and Disease Severity at the Emergency Department
Author(s) -
Fredrik Kahn,
Jonas Tverring,
Lisa Mellhammar,
Nils Wetterberg,
Anna Bläckberg,
Erika Studahl,
Niklas Hadorn,
Robin Kahn,
Susanne Nueesch,
Philipp Jent,
Meret E. Ricklin,
John H. Boyd,
Bértil Christensson,
Parham Sendi,
Per Åkesson,
Adam Linder
Publication year - 2019
Publication title -
shock
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.095
H-Index - 117
eISSN - 1540-0514
pISSN - 1073-2322
DOI - 10.1097/shk.0000000000001332
Subject(s) - medicine , emergency department , organ dysfunction , sepsis , prospective cohort study , biomarker , intensive care unit , oxygen saturation , emergency medicine , intensive care medicine , oxygen , biochemistry , chemistry , organic chemistry , psychiatry
Rapid and early detection of patients at risk to develop sepsis remains demanding. Heparin-binding protein (HBP) has previously demonstrated good prognostic properties in detecting organ dysfunction among patients with suspected infections. This study aimed to evaluate the plasma levels of HBP as a prognostic biomarker for infection-induced organ dysfunction among patients seeking medical attention at the emergency department.