Open AccessMIR-190B Alleviates Cell Autophagy and Burn-Induced Skeletal Muscle Wasting via Modulating PHLPP1/Akt/FoxO3A Signaling Pathway
Author(s) -
Yonghui Yu,
Longlong Yang,
Shaofang Han,
Yushou Wu,
Lingying Liu,
Chonglin Yang,
Xiaoteng Wang,
Jiake Chai
Publication year - 2019
Publication title -
shock
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.095
H-Index - 117
eISSN - 1540-0514
pISSN - 1073-2322
DOI - 10.1097/shk.0000000000001284
Subject(s) - autophagy , protein kinase b , skeletal muscle , microbiology and biotechnology , phosphorylation , chemistry , wasting , pi3k/akt/mtor pathway , burn injury , western blot , endocrinology , medicine , signal transduction , biology , apoptosis , biochemistry , surgery , gene
Cell autophagy is an important material recycling process and is involved in regulating many vital activities under both physiological and pathological conditions. However, the mechanism of autophagy regulating burn-induced skeletal muscle wasting still needs to be elucidated.