Open Access3-Factor Versus 4-Factor PCC in Coagulopathy of Trauma: Four is Better Than Three
Author(s) -
Muhammad Zeeshan,
Mohammad Hamidi,
Narong Kulvatunyou,
Faisal Jehan,
Terence O’Keeffe,
Muhammad Khan,
Lana Rashdan,
Andrew Tang,
El Rasheid Zakaria,
Bellal Joseph
Publication year - 2019
Publication title -
shock
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.095
H-Index - 117
eISSN - 1540-0514
pISSN - 1073-2322
DOI - 10.1097/shk.0000000000001240
Subject(s) - medicine , coagulopathy , intensive care unit , trauma center , injury severity score , propensity score matching , prothrombin complex concentrate , blood transfusion , demographics , surgery , anesthesia , emergency medicine , retrospective cohort study , warfarin , poison control , injury prevention , demography , sociology , atrial fibrillation
Coagulopathy of trauma (COT) is common and highly lethal. Prothrombin complex concentrate (PCC) has been advocated for correction of COT. However, the difference in efficacy between three-factor PCC (3-PCC) versus four-factor PCC (4-PCC) remains unclear. The aim of our study was to compare efficacy of 3-PCC versus 4-PCC in COT.